Seymour works in a skid row florist shop and is in love with his beautiful co-worker, Audrey. He creates a new plant that not only talks but cannot survive without human flesh and blood.

When scientists exploring the Amazon River stumble on a “missing link” connecting humans and fish, they plan to capture it for later study. But the Creature has plans of his own, and has set his sights on the lead scientist's beautiful fiancée, Kay.

Mutated by his own secret formula, Dr. Alec Holland becomes Swamp Thing; a half-human, half-plant superhero who will stop at nothing to rescue government agent Alice Cable and defeat his evil arch nemesis...Even if it costs him his life.