While confronting the disapproving father of his girlfriend Lola, Native American man Willie Boy kills the man in self-defense, triggering a massive manhunt, led by Deputy Sheriff Christopher Cooper.

As the west rapidly becomes civilized, a pair of outlaws in 1890s Wyoming find themselves pursued by a posse and decide to flee to South America in hopes of evading the law.

A mountain man who wishes to live the life of a hermit becomes the unwilling object of a long vendetta by Indians when he proves to be the match of their warriors in one-to-one combat on the early frontier.