Baron Victor Frankenstein has discovered life's secret and unleashed a blood-curdling chain of events resulting from his creation: a cursed creature with a horrid face — and a tendency to kill.

When the Earl of Gurney dies in a cross-dressing accident, his schizophrenic son, Jack, inherits the Gurney estate. Jack is not the average nobleman; he sings and dances across the estate and thinks he is Jesus reincarnated. Believing that Jack is mentally unfit to own the estate, the Gurney family plots to steal Jack's inheritance. As their outrageous schemes fail, the family strives to cure Jack of his bizarre behavior, with disastrous results.

After a spate of murders, the villagers of Schtettel kill the depraved perpetrator, Count Mitterhouse. Fifteen years later the Circus of Nights appeared in the plague-ridden village and its performers include Mitterhouse's mistress, children and cousins. They have come to Schtettel to fulfil the Count's last words, an evil, vicious curse of death and destruction on those who participated in his impaling. The children of Schtettel become the targets for a brutal and devastating revenge as the Vampire Circus rehearses for its most deadly performance.