A group of seemingly humanistic trucks takeover a truck stop and starts killing everything in sight. The remaining townsfolk must band together and come up with a way to murder the inanimate objects, a seemingly difficult task considering the abnormal circumstances.

When a comet passes close to the earth, machines all over the world come alive and go on homicidal rampages. A group of people at a desolate truck stop are held hostage by a gang of homicidal 18-wheelers. The frightened people set out to defeat the killer machines ... or be killed by them.