When foreman Frank shows new employee Freddy a secret military experiment in a supply warehouse in Louisville, Kentucky, the two klutzes accidentally release a gas that reanimates corpses into flesh-eating zombies. As the epidemic spreads throughout the town, and the creatures satisfy their hunger in gory and outlandish ways, Frank and Freddy fight to survive with the help of their boss and a mysterious mortician.

The planned reburial of a village elder goes awry as the corpse resurrects into a hopping, bloodthirsty vampire, threatening mankind. Therefore, a Taoist Priest and his two disciples attempt to stop the terror.

Seymour works in a skid row florist shop and is in love with his beautiful co-worker, Audrey. He creates a new plant that not only talks but cannot survive without human flesh and blood.