Rascal. Joker. Dreamer. Genius... You've never met a college student quite like "Rancho." From the moment he arrives at India's most prestigious university, Rancho's outlandish schemes turn the campus upside down—along with the lives of his two newfound best friends. Together, they make life miserable for "Virus," the school’s uptight and heartless dean. But when Rancho catches the eye of the dean's daughter, Virus sets his sights on flunking out the "3 idiots" once and for all.

After the insane General Jack D. Ripper initiates a nuclear strike on the Soviet Union, a war room full of politicians, generals and a Russian diplomat all frantically try to stop it.

Based on the true story of IPS officer Manoj Kumar Sharma, 12th Fail sheds limelight on fearlessly embracing the idea of restarting the academic journey despite the setbacks and challenges and reclaiming one's destiny at a place where millions of students attempt the world's toughest competitive exam: UPSC.