Carlos is a professionally frustrated screenwriter, and Irene is not sure what she wants to do with her life. When Irene meets Carlos at a coffee shop, she approaches him and, although she doesn't know him, proposes to play a game.

In the late 1800s, a fanatical religious leader, a renegade Sheriff, and a former prostitute collide in a blood triangle on the rugged plains of the New Mexico Territory.

In Bolivia, Butch Cassidy (now calling himself James Blackthorn) pines for one last sight of home, an adventure that aligns him with a young robber and makes the duo a target for gangs and lawmen alike.

Set in Argentina in 1965, the story follows the tumultuous relationship between two men who became lovers and ultimately ruthless bank robbers in a notoriously famous footnote in the annals of crime history. After a large-scale hold-up that turns bloody, the two men must flee. It is not long before the police are surrounding the building they are in and they must confront their demons to survive.