In the near future, writer Victor Banev gets himself on a UN commission to investigate what's going on in the remote town of Tashlinsk, where reports tell of a virus-created race of brainiac mutants. Banev's tween daughter Ira is enrolled at a school for gifted children which has been taken over by the mutants, who have grown to despise ordinary humanity.

Jack Shaw has experienced the terror first-hand. He's a top CIA agent who's tracked international killer-for-hire Carlos "The Jackal" Sanchez for over twenty years and barely survived Carlos' devastating bombing of a Parisian cafe. Now, he finally gets a break when he discovers Carlos' dead ringer: American naval officer and dedicated family man Annibal Ramirez.