Based on the true life experiences of poet Jimmy Santiago Baca, the film focuses on half-brothers Paco and Cruz, and their bi-racial cousin Miklo. It opens in 1972, as the three are members of an East L.A. gang known as the "Vatos Locos", and the story focuses on how a violent crime and the influence of narcotics alter their lives. Miklo is incarcerated and sent to San Quentin, where he makes a "home" for himself. Cruz becomes an exceptional artist, but a heroin addiction overcomes him with tragic results. Paco becomes a cop and an enemy to his "carnal", Miklo.

After a friend overdoses, Spoon and Stretch decide to kick their drug habits and attempt to enroll in a government detox program. Their efforts are hampered by seemingly endless red tape, as they are shuffled from one office to another while being chased by drug dealers and the police.

Chris Anderson and his wife Pam live a fairly normal life until Chris loses his job on the police force and secretly turns to robbing banks to make his wife's dreams come true. Upon discovering his secret, she joins his deadly crime wave and together they terrorize an unsuspecting suburban town.

Aliens punish one of their own by sending him to earth. The alien is very violent, and when the body he occupies is damaged, he is forced to find another.

Wayne Dobie is a shy cop whose low-key demeanor has earned him the affectionate nickname "Mad Dog." After Mad Dog saves the life of Frank Milo, a crime boss and aspiring stand-up comedian, he's offered the company of an attractive young waitress named Glory for a week. At first both are uneasy about the arrangement, but they eventually fall in love. However, the situation becomes complicated when Milo demands Glory back.

In the future, the inmates of a private underground prison are computer-controlled with cameras, dream readers, and devices that can cause pain or death. John and his illegally pregnant wife Karen are locked inside "The Fortress" but are determined to escape before the birth of their baby.

Set during the height of Spanish Inquisition. The beautiful and kind-hearted Maria is arrested as a witch when she inadvertently cries out in horror at the public whipping of a child. As Maria’s husband Antonio tries to save her, Torquemada, the Grand Inquisitor, determines to punish Maria with torture for the desire she inflames in him. Loosely based on Edgar Allen Poe's classic short story.