In the late 1960s, three Harvard students Jessica, Leo and Nick grow close as they undergo personal changes, but their friendship is jeopardized by romantic feelings both men develop for Jessica.

Alex Cross, a genius homicide detective/psychologist is trying to clean up the mean streets of Detroit while keeping his family out of the line of fire. As he mulls over accepting a job with the FBI, he is told that a friend has been murdered and he vows to track down the killer. Soon, he and his team are forced to match wits with a psychotic contract killer, who displays a disturbing commitment towards seeing his job through.