A tough, womanizing high-stakes gambler known only as Tennessee has an uneasy relationship with Duchess, madam of a thinly-disguised bordello, and no other friends at all. But he's saved from murder by a lonesome cowpoke ('My friends call me Cowpoke'), in town to meet his fiancée Goldie on the steamboat. When she arrives, there's a mysterious undercurrent between Goldie and Tennessee, whose newfound friendship with Cowpoke is destined to be severely tried...

In the 1870s, two rival businessmen, Zack Thomas and Joe Jarrett, on a stagecoach heading to Galveston, Texas, must pull together to protect $100,000 from an outlaw named Matson. Once in Galveston, however, their rivalry continues, as Thomas joins up with Elya Carlson and Jarret with Maxine Richter. But Matson is still on the loose, and a scheming banker threatens both Thomas and Jarrett.