Aibileen Clark is a middle-aged African-American maid who has spent her life raising white children and has recently lost her only son; Minny Jackson is an African-American maid who has often offended her employers despite her family's struggles with money and her desperate need for jobs; and Eugenia "Skeeter" Phelan is a young white woman who has recently moved back home after graduating college to find out her childhood maid has mysteriously disappeared. These three stories intertwine to explain how life in Jackson, Mississippi revolves around "the help"; yet they are always kept at a certain distance because of racial lines.

Rachel Watson, devastated by her recent divorce, spends her daily commute fantasizing about the seemingly perfect couple who live in a house that her train passes every day, until one morning she sees something shocking happen there and becomes entangled in the mystery that unfolds.

Sue Ann is a loner who keeps to herself in her quiet Ohio town. One day, she is asked by Maggie, a new teenager in town, to buy some booze for her and her friends, and Sue Ann sees the chance to make some unsuspecting, if younger, friends of her own.

An overlooked pencil-pusher catches her husband in bed with another woman, the shock of which causes him to die of a heart attack. So she buries his body and takes advantage of the growing celebrity status that comes from having a missing husband. But she quickly finds herself in over her head, dodging cops and criminals, all while trying to keep the truth from her sister, a local news anchor who’s desperate for a story.