A brilliant plastic surgeon creates a synthetic skin that withstands any kind of damage. His guinea pig: a mysterious and volatile woman who holds the key to his obsession.

In downtown Madrid, a series of mysterious gunshots trap a motley assortment of people in a decrepit bar.

Sara, Lucía, Sofía and Claudia are sisters, 4 modern women with very different personalities, who come together at their mother's funeral, after which they discover the man they've all called "dad" throughout their lives is not really their father. They embark on a quest to discover who their real fathers are, discovering more about themselves, their mother, and their lives.

In 1920s Madrid, four women at the National Telephone Company ring in revolution as they deal with romance, envy and the modern workplace.