Let's Go, Grandma! plays like an exuberant, goofy update to Yasujiro Ozu's Tokyo Story. Kinuyo Tanaka plays the titular Grandma, who, after selling her Hokkaido property, is apparently flush with cash but newly homeless. Her grown children take turns hosting her, making extravagant performances of filial devotion with an eye to potential profit. Making use of a catalog of wacky visual effects, bracketed by gratuitous ham-fisted fight scenes, and costarring pop singer Hideki Saijo, the film is balanced by Tanaka's nuanced performance, which delivers a denunciation of hypocrisy and greed.

21-year-old Hideo Ishida is a reckless young man. Today again, he took part in a car race with a stolen driver's license and a car belonging to the junkyard. But unfortunately, things go wrong and after a collision with another car, the seriously injured Hideo is taken to the hospital. Here he meets the nurse Yuki Kobayashi. Yuki is the opposite of Hideo. During the day she works as a nurse and in the evening she studies hard. However, Hideo's behavior leaves an unforgettable impression on Yuki and the two soon develop an intimate friendship ...