Deep within the Hidden Leaf Village, young ninja Naruto Uzumaki carries sealed inside him the Nine-Tailed Fox Spirit, which once almost destroyed the village. Always an outcast because of his secret, now Naruto battles alongside his teammates Sasuke and Sakura to prove to himself and everyone else that he's the greatest ninja ever. But he's got a long list of challenges to face before he gets there!

The story takes place in 19th century Europe, and revolves around John Watson. He is scouted by the government to become a secret agent. However, Watson lives in a world where "Frankensteins"—human corpses that are re-purposed with a false soul in order to use them as laborers—are used to improve industrial development.

A Russo-Japanese War veteran partners with an Ainu girl to find a treasure stolen from her people, but they’re not the only ones pursuing the gold.

中世纪，炼金术士们以巨大的代价从恶魔的手中得到了传说中的永生之酒，凡是喝下永生之酒的人们，正如它的名字那样，将会得到永远不会死亡的肉体。永生之酒带来了希望，却也引发了空前绝后的灾难，因为私欲和利益，与此酒相关的人士一个接着一个失去了踪迹。随着禁酒令的颁布，永生之酒的下落逐渐成为了谜题，然而数年过后，有关它重出江湖的消息再次被传得沸沸扬扬，在纽约的黑道中激起了涟漪。
身怀绝技的少年洛菲（吉野裕行 配音）、不老不死的炼金术士阿洛瓦（宫本充 配音）、个性莽撞大大咧咧的夫妻艾萨克（小野坂昌也 配音）和哈文特（青木静香 配音），这些身份从无交集的人们，也为了追寻永生之酒的下落而走到了一起。

Break-dancing but fierce warrior Mugen has to deal with the cold-blooded and conceited Jin, a samurai who believes he is above all. These sworn enemies are brought together by Fuu for a special task.