So long as people have hearts, there will be those with worries and concerns. Those hearts are then invaded by something strange, causing them to show strange physical symptoms. These ailments, called "mysterious diseases", exist unseen to most people. Modern medicine offers no cure, but there is one doctor who fights these diseases along with his pupils. His name is Ramune. He looks nothing like a doctor, is foul-mouthed, and does whatever he pleases, but he has the ability to pinpoint the cause of the troubles hidden deep within his patients' hearts and cure their mysterious diseases.

During the Warring States era, the feuding generals were suddenly struck down one after another by the demonic Kishin. In the 150 years since, groups of individuals have continued to resist Kishin control. They are called Bushi bands. When they were young, Musashi and Kojiro would hear tales about the Bushi from Kojiro's father, and the two of them dream to form the strongest Bushi band. One day, as Musashi struggles with his choices, he witnesses humans being torn apart by oni. Forced to face the truth, Musashi rises up against the powerful oni to make his dream with Kojiro come true!

The Far Eastern Special Administrative Region, also known as the 24th Ward, is a man-made island. Shuta, Ran, and Koki were born and raised on the island. Their family backgrounds, preferences, and personalities are completely different, but they always stuck together. However, one incident changed their relationship forever. A year afterward, the three friends are reunited by chance at a memorial service held for the incident. All three of their phones suddenly ring simultaneously. Their friend, who is supposed to be dead, is calling and demands that they make a decision about the future.

The Lost Ones are wanderers who come here from a distant world known as "Japan." No one knows how or why they leave their homes. The only thing that is certain is that they bring disaster and calamity. The duty of exterminating them without remorse falls to Menou, a young Executioner. When she meets Akari, it seems like just another job...until she discovers it's impossible to kill this girl! And when Menou begins to search for a way to defeat this immortality, Akari is more than happy to tag along! So begins a journey that will change Menou forever...

What would you do to pursue your passion? For Hiyori Suzumi, it’s leaving her simple rural hometown for the bustling city of Tokyo to join Sakuragaoka High School’s track team. Between being a manager-in-training for two cutthroat schoolboy idols, track, and friends, Hiyori shows no signs of slowing down.

Asahi, a boy who loves video games is killed in a traffic accident and ends up in another world. He tries to enjoy the otherworldly adventuring life he's always dreamed of, but his stats are on the level of an NPC's. He is in big trouble and is being chased by a monster when he hears, "Fear not, little brother!" and the monster is killed in one hit by Asahi's older sister, Maya, who followed Asahi to this world. So Maya has acquired some seriously OP skills, but she takes her adoration of her younger brother to extremes. Thus begins their story about an overpowered older sister with a brother complex and a younger brother with the weakest of stats in another world.

After being fired from his detective job, Brian receives a strange letter. He heads to the address written on the envelope and finds himself among the Marginal Service! This motley crew of fearless men and a woman (and a squirrel) are tasked with hunting down aliens. And Brian just became their newest member.

As a legendary hero nears victory against a necromancer known as The Corpse God, things take an unexpected turn with the dark sorcerer’s final gambit—reincarnation magic. This last-ditch effort catches the brave fighter off guard, and now he’s a boy named Polka Shinoyama in a whole new world! The showdown between good and evil just got epic.

This college kid wants nothing more than a quiet life. So when she's reborn as Yumiella, the hidden villainess of an Otome RPG, she's not exactly thrilled. Still yearning for peace, she abandons her evil duties to live a more discreet life. Until her gamer side kicks in, and she accidentally reaches level 99! Now, everyone suspects that she's the infamous Demon Lord. What future awaits her?

After surviving the entrance exams, Sakuta Azusagawa has finally enrolled in the same university as his girlfriend, Mai Sakurajima. He is gradually getting used to the unfamiliar environment as he attends student gatherings and makes new acquaintances. Everything seems to be going smoothly until Sakuta's friend and Sweet Bullet idol group member Uzuki Hirokawa begins acting out. With fellow Sweet Bullet member Nodoka Toyohama pleading for his help, Sakuta realizes that he has stumbled upon another case of the inexplicable Puberty Syndrome-Uzuki is feeling pressured by the sudden surge of popularity and rumors of a potential solo career. While Sakuta searches for a solution, another occurrence of Puberty Syndrome gradually emerges from the shadows.

As Sasaki prepares for his college entrance exams, Miyano tries to make the most of their limited time together while grappling with his own emotions.

Japanese anime television series

Azumaya and Takato are set to star in "Blood Wedding," a two-person play that incorporates flamenco dancing; Takato decides to travel to Spain to learn about passion.

"I'll make it so your body's unable to forget mine." Saijou Takato's 5 year reign as the 'Most Huggable No. 1' has been snatched. Stealing his thunder is the newbie actor with a 3-year debut, Azumaya! Towards the stuffy hostile Takato, Azumaya's sincere sparkling smile starts to become effective. Even as Takato sets his alert level on MAX, Azumaya catches Takato in his shameful drunken state and uses it to blackmail him! In exchange for Azumaya's silence, Azumaya states, "Please let me hold you…?! Embrace me, who was the Most Huggable No.1?" What the heck is he saying! Includes a large quantity of other high suspense erotic stories.

given gains buzz after a failed audition, but things get complicated when Ritsuka is asked to play for Mafuyu’s old friends’ debut show.

Mafuyu doubts his place in the band, but a familiar face could be the spark that brings him back to the stage.

Kaboku has always just gone with the flow, marching in step to the drumbeat of the expectations of those around him: parents, school, plans for the future. It feels predictable, safe, and… empty. But one night, Kaboku's at school late, and he happens on a girl alone, moving wildly, turning a blank space of concrete into a canvas. This is Hikari Wanda, a member of the hip-hop dance club. Kaboku is immediately smitten, but the road to stepping out of his shell is a long one. The club is almost entirely girls, and they're all, well, way better than him. What's ahead is unknown, and that's terrifying, but it also means, for the first time in Kaboku's life… a taste of freedom.

"This is my punishment - someone as hideous as me falling for someone as good-looking as you..." Yumeko had a mountain of complexes about herself. Then, a terrible accident befalls her. Though somehow saved from the brink of death, Yumeko wakes up a completely different person. "Is this...me...?! I'm SUPER cute!!" Those around her can't hide their surprise and wonderment at this 180-degree change... But, Yumeko's new hyper-positive attitude starts to change her surroundings, too. Worries and complexes can affect anyone, and Yumeko will chop right through those of her various supporting characters!! In love, work, friendship... And an attempted murder case?!

A gifted runner trains a determined but unskilled classmate, unaware he's creating a rival who will challenge him on the track for years to come.

After losing her grandfather, Aoi—a girl who can see spirits known as ayakashi—is suddenly approached by an ogre. Demanding she pay her grandfather’s debt, he makes a huge request: her hand in marriage! Refusing this absurd offer, Aoi decides to work at the Tenjin-ya bed and breakfast for the ayakashi to pay back what her family owes.