A range war between cattlemen and farmers comes to a head with the arrival of a Deputy Marshal and "Mule" a famous gunfighter in the town of Houstonville, Texas.

An American narcotics agent is murdered in Italy. The head of the department decides to hire Larry Stanziani, 'The Cobra'. Larry, a former agent and now a third-rate private detective, uses the opportunity to get even with an old enemy, but soon he finds out he's facing a relentless organization

Stefano Augenti, an ambitious advertising executive, meets a curious hippie named Count Mateo Tiepolo and they form a strange bond. Seeking an escape from his unhappy marriage, Augenti is lured by the Count into a bizarre plot to kill each other's relatives.