Bem, Bela, and Belo are not "monsters," nor "humans," but "humanoid monsters." They usually disguise themselves as a human family living together, but their appearances transform into ugly monsters when their emotions become uncontrollable due to intense anger or extreme sorrow. Even if they save humans out of a sense of justice, they are feared and hated by humans just because they are humanoid monsters. They have lived in this manner for centuries, and their only wish is to become humans as soon as possible. One night, Bem saves a man, and becomes friends with detective Natsume. At Natsume's house, he finds a photo of a man who may hold a clue as to how to become humans. They go to meet the man, Ogata, who denies any knowledge and disappoints them. Meanwhile, the case of the man Bem had saved, rapidly unfolds, and Natsume finds himself in trouble. Can Bem save Natsume?! Will Bem and his sidekicks' dream come true?!

Makoto Masaki and Haruko Kogetsu are both 29 years old and single. Since they were children, they have passed each other at various places like on the beach and shrines. Yet, the two are not aware of each other at all. One day, a man appears in front of Makoto Masaki and introduces himself as God. He tells Makoto Masaki about his destined soul mate and that she works next door. When he faces Haruko Kogetsu, he tells her "I'm your destiny."

Hatanaka Kosaku is a talented boxer who turned pro at the age of 19, winning his debut match with a first round KO. He is talented, but he has no guts. His uncontrollable appetite is an even bigger problem. He can't put himself in the right weight class, he runs out of energy because of hunger, and he gets knocked out while his eyes are set on food at the ringside. However, Kosaku's life changed when he met Sister Angela, a novice nun in the convent near his boxing gym. She became the source of his power, and Kosaku fights only to win her heart.

Sunako is very happy living her life in the darkness of her room, with her skeleton friends and her horror movies to keep her company. The darkness she so loves is pierced brightly by four dazzling young men, who come to live in the same mansion as her, and she soon realizes that they have orders from her aunt to do anything to turn her into a prim and proper lady.

In an alternative feudal Japan, a strange disease that only affects males caused a massive population reduction, leaving females to fill the vacant jobs, therefore changing the social structure. Now, 80 years after the initial outbreak with a 1:4 male:female ratio, Japan is a completely matriarchal society. Females hold all important political positions, and males are their consorts. Only the most powerful female—head of Tokugawa shogunate—may keep a harem of handsome and unproductive males, known as "Ōoku".

When world-renowned wine critic Toyotaka Kanzaki passes away, he leaves behind an enviable collection. The will promises his estate to whoever correctly guesses the brand and year of the 12 greatest wines he selected, and the legendary wine that stands atop them all, "Drops of God." The challengers are Toyotaka's son, Shizuku Kanzaki, and a young critic, Issei Tomine, who was adopted by Toyotaka.