After killing a prison guard, convict Robert Stroud faces life imprisonment in solitary confinement. Driven nearly mad by loneliness and despair, Stroud's life gains new meaning when he happens upon a helpless baby sparrow in the exercise yard and nurses it back to health. Despite having only a third grade education, Stroud goes on to become a renowned ornithologist and achieves a greater sense of freedom and purpose behind bars than most people find in the outside world.

After killing her husband, Peggy Gravel and her murderous maid Grizelda wind up in the crazy town of Mortville, where Queen Carlotta presides over a sleazy collection of misfits.

Notorious Baltimore criminal and underground figure Divine goes up against Connie & Raymond Marble, a sleazy married couple who make a passionate attempt to humiliate her and seize her tabloid-given title as "The Filthiest Person Alive".

A spoiled schoolgirl runs away from home, gets pregnant while hitchhiking, and ends up as a fashion model for a pair of beauticians who like to photograph women committing crimes.

The Cavalcade of Perversion, a traveling freak show, acts as a front for Divine, who is out for blood after discovering her lover's affair.

A day in the lives of a hit-and-run driver and her victim, and the bizarre things that happen to them before and after they collide (sexual assault by a crazed foot-fetishist, visions of the Virgin Mary, strange chicken-foot grafting operations).

An incomplete project, Dorothy the Kansas City Pothead stars John Waters' long-time casting agent Pat Moran in the role of Dorothy.

Shot on 8mm, and featuring the introduction of Divine, John Waters' sophomore film is a plotless collage of random incidents involving sex, drugs, religion and The Wizard of Oz, it was shown with an equally random soundtrack mixing “obnoxious radio advertisements, rock 'n' roll and press conferences with Lee Harvey Oswald's mother”. It was shown three times publicly, but never released commercially.

A documentary about actress Edith Massey in which she talks about her life and her career in film.

Harris Glenn Milstead, aka Divine (1945-1988) was the ultimate outsider turned underground hero. Spitting in the face of the status quos of body image, gender identity, sexuality, and preconceived notions of beauty, Divine succeeded in becoming an internationally recognized icon, recording artist, and character actor of stage and screen. Glenn went from the often-mocked, schoolyard fat kid to underdog royalty, standing up for millions of gay men and women, drag queens and punk rockers, and countless other socially ostracized misfits and freaks. With a completely committed in-your-face style, he blurred the line between performer and personality, and revolutionized pop culture.