Last season, House and Cuddy finally decided to take their relationship to the next level, but struggled to find a balance between their professional and personal lives, and ultimately, Cuddy made the very emotional decision to end their relationship. As each of them dealt with the aftermath of the break-up, House got married to an immigrant in need of a Green Card. In the series' milestone 150th episode, Thirteen was released from prison after euthanizing her brother who was suffering from the late stages of Huntington's Disease, the same disease with which she is afflicted. As the season comes to a close, when House's attempts to mend his relationship with Cuddy fall short, he's compelled to take drastic and possibly irrevocable measures that could forever change the course of their relationship.

When the previous season concluded, House was forced to admit that he had lost his grip on reality and could no longer practice medicine. Out of options, he checked himself into a psychiatric hospital. Season 6 will explore House’s long and twisted road to recovery: Can he find some version of sanity and normalcy? Can he stay away from the workplace that arguably drove him to mental instability but is also the only stable foundation in his life? Can Princeton-Plainsboro continue its celebrated Department of Diagnostics without him? How will Cuddy’s relationship with House change, now that their imagined affair is out in the open?

A British comedy television series with turns of phrase and elaborate wordplay, written by and starring former Cambridge Footlights members Stephen Fry and Hugh Laurie.