The future’s looking bleak. It’s a good thing there’s a new sheriff in town. Her name is Jo and she’s an enigma even to herself. Alongside her partners Sei, Amy, and Meg, Jo fights for the citizens who can’t defend themselves. Confronting corruption and twisted science, these gals are on fire—and they’re the best chance the wounded city’s got.

In the midst of societal conflict in the futuristic city of Metropolis, Kenichi and his uncle Shunsaku Ban set out to uncover the mystery behind the first human-like robot, Tima.

因为父母被调往了海外就职，不想跟着出去的相泽佑一（杉田智和 配音）寄宿到了阿姨水濑秋子和她女儿名雪家里。时隔七年，再次来到这个北国小镇的佑一本应有记忆点，可是真实的情况确是毫无记忆。在这个小镇，他邂逅了各色少女。有总是元气满满、迷糊的月宫亚由（堀江由衣 配音）；有擅长料理喜爱猫咪的名雪（国府田麻理子 配音）；有丧失掉记忆，总是对佑一纠缠不休的泽渡真琴（饭冢雅弓 配音）；还有佑一身体不好安静的学妹美坂栞（佐藤朱 配音）等。佑一和她们在北国小镇度过了欢乐的冬天，并且一点点拾回失去的记忆。而这失去的记忆里，有悲伤、悔恨、眼泪……经过时间的洗礼，伤痛在一点点愈合。冬天已走，春天不远。
本片改编自Key社的同名游戏。2002年由东映动画制作成动画上映，这部由京都动画重制。

A group of mysterious white-haired children has been spotted at different times and places in Europe for over 500 years. Always with the looks of 11 years old, they behave way more mature than they should be, never grow, and seem to have supernatural power. What they have kept being after is a girl, and all the connection they have is a picture with a crescent moon. Now, in the year of 2012, an athletic boy named Tohma is about to be involved in this centuries-long mystery.