After a series of brutal, unexplained murders in a remote forest, a rogue military unit is recruited to hunt for whoever - or whatever - has rendered the attacks. In order to carry out the investigation, they need the help of the only survivor, Kate. But first they have to get her released from the mental institution she's been confined to since the horrific attack.

Deadly spiders are accidentally unleashed from a top-secret military installation. Army specialists and Tanks are called in to exterminate the deadly predators, but the outbreak is worse than expected. Weapons of mass destruction have little or no effect on the venomous spiders. Civilians are strangled with spider webs and eaten alive. The Military in a desperate effort to eradicate the killer spiders, decide to demolish the entire city.