One day, 14-year-old Yusuke Urameshi suddenly finds himself dead, having died pushing a child out of the way of oncoming traffic. Since he has such a bad personality, even the Spirit World was caught by surprise that he would sacrifice himself. Yusuke soon finds out he wasn't supposed to die and has a chance for resurrection and bringing his body back to life. After being resurrected, Yusuke becomes a Spirit Detective, along with his comrades, and one adventure after another happens, whether it be an investigation or a fighting tournament.

自古妖魔侵入人类的世界，化作人形并以吞食人类的内脏为生，对妖魔束手无策的人类唯有求助于身背巨剑的女性战士们。因为战士们是由于体内混合了妖魔的血肉才得到超人的力量，所以人类同样将她们视为异类，一方面依靠着她们斩杀妖魔，一方面畏惧并排斥着她们，并将她们称为“Claymore（大剑）”。 当妖魔的出现打破了一个普通山村的平静生活，万般无奈的村长只好求助于大剑组织。一位面容冷酷的战士接受委托来到这里，由此拉开了这场波澜壮阔的故事序幕。

Gameoverse is an animated series about VIDEO GAME WORLDS!!!... Horrifically exploding. And saving them means helping the bad guy stop the good guy or everyone dies.