Ami's friend, Yoshie, was murdered and desecrated by the Kimura Gang. She was saved and, like Ami in the previous film, received modifications from the same mechanics. Remembering her past, Yoshie decides to avenge herself and Ami.

When a mysterious loner and Karate master Kenji's little sister goes missing in Los Angeles, whoever stands in his way of finding her will face the wrath of a lethal KARATE KILL!

A brilliant doctor on a quest for revenge buys a young woman and trains her to be the ultimate assassin, implanting gun parts in her body that she must later assemble and use to kill her target before she bleeds to death.