Two young Chicago hoodlums, Tom Powers and Matt Doyle, rise up from their poverty-stricken slum life to become petty thieves, bootleggers and cold-blooded killers. But with street notoriety and newfound wealth, the duo feels the heat from the cops and rival gangsters both. Despite his ruthless criminal reputation, Tom tries to remain connected to his family, however, gang warfare and the need for revenge eventually pull him away.

New York singer and nightclub owner Lady Lou has more men friends than you can imagine. One of them is a vicious criminal who’s escaped and is on the way to see “his” girl, not realising she hasn’t exactly been faithful in his absence. Help is at hand in the form of young Captain Cummings, a local temperance league leader.