Director Rowland V. Lee's wacky 1942 comedy, about an absent-minded scientist working on a secret formula at an explosives plant, stars Edmond O'Brien, Victor McLaglen, Dorothy Lovett, June Havoc, Eddie Foy Jr., Marion Martin and Mary Gordon.

Henry Stephenson stars as a retired Scotland Yard detective. He is regarded as an icon because he has written volumes of books on the art of detection. While Stephenson is being honoured for his past successes, he senses modern detectives, particularly the current District Attorney, look at him and his methods as outdated. This spurs the old man out of retirement to prove himself to the know-it-all modern detectives.

Lucky Devils casts the mismatched duo as a pair of intrepid newsreel cameramen. When they're not risking their lives coverning the Hot Spots of the world, Dick (Arlen) and Andy (Devine) busy themselves romancing Norma (Dorothy Lovett) and Gwendy (Janet Shaw), respectively.