Twelve people are aboard Coast Airline's flagship the Silver Queen enroute to South America when the airplane encounters a storm and is blown off course. Crashing into jungles known to be inhabited by head hunters, pilots Bill and Joe race against time to fix the engines and attempt a take off. The situation brings out the best and worst in the stranded dozen as they create a makeshift runway and prepare to escape before the natives attack. But damage to the plane and low fuel reserves means that only 5 people can be carried to safety.

A South American plane loaded with an assortment of characters crash lands in a remote jungle area in the middle of a storm. The passengers then discover they are in an area inhabited by vicious cannibals and must escape before they are found. A remake of Five Came Back (1939).