Conan O'Brien visits new friends he met through his podcast, "Conan O'Brien Needs a Fan," where he dives deep with listeners from across the country and the world.

Stepping into the late-late slot vacated by David Letterman, Conan O'Brien stars in a show that far outdoes its competition in sheer strangeness. Along with the celebrity interviews and musical numbers typical of late-night talk shows, this program make frequent use of odd walk-on characters and frequent "visits" from celebrity guests.