故事发生在伊斯坦布尔，在夜幕的笼罩下，东方快车在黑暗里静静的等待着乘客们的到来，准备启程，其中，就有大名鼎鼎的波洛神探（阿尔弗雷德·莫里纳 Alfred Molina 饰）。第二天早上，商人雷切特（彼得·斯特劳斯 Peter Strauss 饰）在餐车里找到了波洛，说他收到了一封匿名的威胁信，信中号称有人想要夺走他的性命。雷切特希望波洛能够保护自己的生命安全，然而，波洛甚至雷切特是一个恶行累累的小人，可以为了获得金钱而无所不用其极，他当然拒绝了雷切特的请求。
当夜，雷切特被人发现死在了自己的车厢里，波洛开始着手调查此案。在和列车里的所有乘客交谈过后，波洛发现，雷切特的死和多年前的一宗儿童绑架案有着千丝万缕的关联。

Bret Maverick is a gambler who would rather con someone than fight them, and needs an additional $3k in order to enter a winner-takes-all poker game beginning in a few days. He joins forces with a woman with a marvelous Southern accent, and the two try and enter the game.

Peter Parker is going through a major identity crisis. Burned out from being Spider-Man, he decides to shelve his superhero alter ego, which leaves the city suffering in the wake of carnage left by the evil Doc Ock. In the meantime, Parker still can't act on his feelings for Mary Jane Watson, a girl he's loved since childhood. A certain anger begins to brew in his best friend Harry Osborn as well...

Donald Trump has it all. Money, power, respect, and an Eastern European bride. But all his success didn't come for nothing. First, he inherited millions of dollars from his rich father, then he grabbed New York City by the balls. Now you can learn the art of negotiation, real estate, and high-quality brass.

A murder in Paris’ Louvre Museum and cryptic clues in some of Leonardo da Vinci’s most famous paintings lead to the discovery of a religious mystery. For 2,000 years a secret society closely guards information that — should it come to light — could rock the very foundations of Christianity.

Harvard symbologist Robert Langdon is recruited by the Vatican to investigate the apparent return of the Illuminati – a secret, underground organization – after four cardinals are kidnapped on the night of the papal conclave.