After the death of his wife, world-class neurosurgeon Dr. Andrew Brown leaves Manhattan and moves his family to the small town of Everwood, Colorado. There he becomes a small-town doctor and learns parenting on the fly as he raises his talented but resentful 15-year-old son Ephram and his 9-year-old daughter Delia.

Season 2 will pick up where Season 1 left off. Mizu has travelled to London with an imprisoned Abijah Fowler in tow, searching for the two other white men that could be her father.

Driven by a dream of revenge against those who made her an outcast in Edo-period Japan, a young warrior cuts a bloody path toward her destiny.