A group of scientists in San Francisco struggle to stay alive in the aftermath of a plague that is wiping out humanity, while Caesar tries to maintain dominance over his community of intelligent apes.

A highly intelligent chimpanzee named Caesar has been living a peaceful suburban life ever since he was born. But when he gets taken to a cruel primate facility, Caesar decides to revolt against those who have harmed him.

Against the vibrant backdrop of a 1960s-inspired, retro-futuristic world, Marvel's First Family is forced to balance their roles as heroes with the strength of their family bond, while defending Earth from a ravenous space god called Galactus and his enigmatic Herald, Silver Surfer.