In the mid-19th century, Senator William J. Tadlock leads a group of settlers overland in a quest to start a new settlement in the Western US. Tadlock is a highly principled and demanding taskmaster who is as hard on himself as he is on those who have joined his wagon train. He clashes with one of the new settlers, Lije Evans, who doesn't quite appreciate Tadlock's ways. Along the way, the families must face death and heartbreak and a sampling of frontier justice when one of them accidentally kills a young Indian boy.

Former DEA Agent Quinlan, removed from the force some years earlier for stealing confiscated drug money, is hired by Chung Wei, a leader in the Amsterdam drug cartel, who wants out of the business. Quinlan's job is to use Chung's information to tip DEA agents to drug busts, thereby destroying the cartel. But when the first two "tips" go awry, resulting in murdered DEA officers, the feds must decide whether to trust Quinlan further...

The peaceful life of a gas station owner is disrupted when a man from his past arrives in town and forces him to return to the dark world he had tried to escape.