After learning that an old friend of theirs has been arrested in Morocco on drug charges, four former college buddies set out for Marrakech to bail him out.

Two actors leave on a theatrical tour, but there is a matter to be settled: one has become the lover of the other's girl-friend and since they are very good friends, cannot bring himself to tell him.

Mario works in a Milan bank. His daily routine is shattered when he witnesses a murder committed by a deranged police commissioner. To save his life, he flees to Puerto Escondido, Mexico. When he runs out of money he teams up with Alex and Anita, a couple of Italians that will lead him on to a series of adventures and encounters with drug dealers, corrupt police officers and other weird characters.