Hitman Martin Blank becomes a moving target after he rebuffs a fellow assassin's invitation to form a union. On the advice of his quirky assistant and neurotic psychiatrist, Martin begrudgingly heads out to Grosse Pointe, Michigan for his ten-year high school reunion, where he soon comes across the woman he jilted on prom night.

Unscrupulous boxing promoters, violent bookies, a Russian gangster, incompetent amateur robbers, and supposedly Jewish jewellers fight to track down a priceless stolen diamond.

Lou Diamond Phillips and Fred Gwynne team up with a gang of professional criminals who have everything it takes to rob a bank. The only things they do have going for them are a cop and his partner, who are dumber than they are! By the time the gang hits the bank vault, it's a safe bet there's going to be organized insanity and disorganized crime!