Rogue is a "Genetic Infantryman", a genetically-engineered, blue-skinned, manufactured super soldier who, alongside his three comrades, is searching for the Traitor General. His comrades are with him in the form of biochips—onto which a G.I.'s entire personality is downloaded at the time of death for later retrieval—and are named Gunnar (mounted on Rogue's rifle), Bagman (on his backpack) and Helm (on his helmet). Rogue is designed to be immune to almost all known toxins, can submerge in strong acid unaffected, and is able to withstand a vacuum on his bare skin.

Yuki's family is nearly wiped out before she is born due to the machinations of a band of criminals. These criminals kidnap and brutalize her mother but leave her alive. Later her mother ends up in prison with only revenge to keep her alive. She creates an instrument for this revenge by purposefully getting pregnant. Yuki never knows the love of a family but only killing and revenge.

The Swamp Thing returns to battle the evil Dr. Arcane, who has a new science lab full of creatures transformed by genetic mutation, and chooses Heather Locklear as his new object of affection.