Set in the year 2000, when the level of Labor accidents begin to escalate around Tokyo Bay, police detectives Kusumi and Hata are assigned to investigate. What they discover leads to a series of government cover-ups, conspiracy concerning a new biological weapon entitled WXIII-Wasted Thirteen and a tragic, personal connection to Hata. The only hope to stop this threat is to cooperate with the military and lead WXIII into a showdown with the Labors of Special Vehicle Division 2.

In the city of Shinjuku, a conflict between a rouge Karas by the name of Eko and the "will of the city" rage in a conflict for dominance. A Karas brought about to fight the rouge has fallen, leaving the city and its inhabitants defenseless. Soon after, Otoha, a comatose patient, is chosen to become a new Karas to face off the rouge Karas Eko to decide the fate of the city and its inhabitants.

Mirage of Blaze is a shōnen-ai light novel series by Mizuna Kuwabara, which are published under Shueisha's Cobalt label. It was adapted into an anime TV series directed by Susumu Kudo in 2002 and an OVA in 2004.

Difficult to classify, Mirage of Blaze is equal parts melodrama, historical romance, and supernatural fantasy. Japanese history predominates a heavily structured plot, which mainly involves the continued aggression between magic using guardians, or "possessors," and the denizens of a "feudal underworld," or the restless souls of long-dead samurai attempting to re-ignite ancient war on the modern plane.

The anime TV series and the OVAs have since been released in North America by Media Blasters, and both have aired on Encore Action and Encore WAM.