Agents J and K are back...in time. J has seen some inexplicable things in his 15 years with the Men in Black, but nothing, not even aliens, perplexes him as much as his wry, reticent partner. But when K's life and the fate of the planet are put at stake, Agent J will have to travel back in time to put things right. J discovers that there are secrets to the universe that K never told him - secrets that will reveal themselves as he teams up with the young Agent K to save his partner, the agency, and the future of humankind.

After a police chase with an otherworldly being, a New York City cop is recruited as an agent in a top-secret organization established to monitor and police alien activity on Earth: the Men in Black. Agent K and new recruit Agent J find themselves in the middle of a deadly plot by an intergalactic terrorist who has arrived on Earth to assassinate two ambassadors from opposing galaxies.

Kay and Jay reunite to provide our best, last and only line of defense against a sinister seductress who levels the toughest challenge yet to the MIB's untarnished mission statement – protecting Earth from the scum of the universe. It's been four years since the alien-seeking agents averted an intergalactic disaster of epic proportions. Now it's a race against the clock as Jay must convince Kay – who not only has absolutely no memory of his time spent with the MIB, but is also the only living person left with the expertise to save the galaxy – to reunite with the MIB before the earth submits to ultimate destruction.

A research chemist comes under personal and professional attack when he decides to appear in a 60 Minutes exposé on Big Tobacco.