A wealthy woman from Manhattan's Upper East Side struggles to deal with her new identity and her sexuality after her husband of 16 years leaves her for a younger woman.

A gifted high school student steals plutonium from the secret nuclear weapons facility in his home town in order to construct his own nuclear bomb, win a national science fair, and expose the government's secrets.

Arthur is a 30-year-old child who will inherit $750 million if he complies with his family's demands and marries the woman of their choosing.

A divorced writer from the Midwest returns to her hometown to reconnect with an old flame, who's now married with a family.

Though Rachel is a successful attorney and a loyal, generous friend, she is still single. After one drink too many at her 30th-birthday celebration, Rachel unexpectedly falls into bed with her longtime crush, Dex -- who happens to be engaged to her best friend, Darcy. Ramifications of the liaison threaten to destroy the women's lifelong friendship, while Ethan, Rachel's confidant, harbors a potentially explosive secret of his own.

While at an impromptu reunion lunch, five women reminisce and relive their college days at Mount Holyoke, and weigh their goals and aspirations against their lives.