Fearful that their star witness might be murdered, two attorneys hire a protector to bring him from Los Angeles to New York. Jesse Crowder (Fred Williamson) is a no-nonsense tough guy. He buddies up with the witness, an accountant, and they hit the road. Outwitting their foes means taking all manner of conveyance, including automobile, train, and airplane.

A man, Dr. Fez, is blackmailed into taking a fall for his boss. However, with a cruel invention that he created, Dr. Fez has plans of his own to seek revenge against his blackmailer.