Investigators Conrado and Fernando take a leave of the absence from the police force to track down Fernando's girlfriend Virginia. Virginia, a reporter, has left town and is working undercover as a barmaid in order to interview Refugio Canales, a criminal and small town municipal president. Conrado and Fernando soon call their friend Santo for help.

Tourists visiting the pyramids in Mexico experience a string of deaths and disappearances while staying at a nearby hotel. Police investigators Fernando and Cornado are assigned to the case and attempt to solve the mystery with the help of reporter (and girlfriend of Fernando) Veronica and the wrestler Santo.

Masked luchador "Santo" fights against an evil doctor and his zombie army.