Spurred on by the death of his drug-addicted sister at the hands of ruthless narcotics kingpin Frank McNally, U.S. drug enforcement agent Charles Sturgis embarks on an investigation that takes him from New York to London, Lisbon, Rome, Naples and finally Athens in pursuit of McNally's shapely associate, Gina Broger.

Tabitha, once the placid, gentle and devoted pet, adopts all the characteristics of a ferocious, wild animal following the murder of her mistress. The three guilty people are all trapped by the cat's power and each will come to untimely deaths of horrific proportions without anyone being able to solve the mystery that surrounds their brutal death.