A serpentine day in the life of ten seemingly disparate women: a porn star, a flight attendant, a psychiatrist, a masseuse, a bartender, a pair of call girls, etc. All of them with one crucial thing in common. Trouble.

A reporter on the trail of a sinister cult wakes up in a morgue to find herself a member of the undead. She goes on a personal vendetta against a group a cultists who are responsible for her death.

The newly married Elizabeth arrives with her new husband, the scientist Henry, at a magnificent house. He tells her that she can do there anything she pleases, except to enter a certain closed room.

A woman (Carla Gugino) and her lover (Simon Baker-Denny), who has made a living by running sex scams at hotels, decide to enter the big time by kidnapping a computer company owner (Greg Wise) and demanding $4 million ransom. The two hire a tech wizard (Gil Bellows) and a muscle man (Til Scweiger), who amuses himself by playing Russian roulette. Things go awry during the kidnapping when a neighbor is killed, who turns out to be the wife of a powerful senator (Hal Holbrook). As things develop, it turns out that the murder may not have been as accidental as it originally appeared. Slowly things unveil to not to be everything that was originally thought.