An updated version of the classic horror tale by Edgar Allen Poe. Ryan and his girlfriend Molly are going to visit Ryan's uncle, Roderick Usher, at his mansion. They find, however, that Roderick's brother Walter has gone insane, and Roderick himself isn't far behind. Can Ryan and Molly escape from the doomed mansion before the curse of Usher claims them as well?

Ex-DEA agent Jack receives an emergency message from his brother Phillip, whose team was ambushed on the Caribbean island of St. Keith. Jack goes to St. Keith to find his brother, who has been turned into a cyborg by the drug runner he was after.