L'histoire de quarante ans de musique à travers les yeux de Richie Finestra, un producteur de disques qui tente dans les années 70 de faire renaître de ses cendres son label en trouvant de nouveaux sons et de nouveaux talents alors qu'il traverse sa crise de la quarantaine. Drogue, sexe, punk et disco deviennent son quotidien...

After her husband deserts her, working-class mother Ray Eddy is in great need of money to find a home. Lured by the possibility of easy cash, she joins Lila, a widowed Mohawk who earns a living by smuggling immigrants from Canada to the U.S. across the St. Lawrence.

Eloise, having been relieved of maid of honor duties after being unceremoniously dumped by the best man via text, decides to attend the wedding anyway – only to find herself seated with five fellow-unwanted guests at the dreaded Table 19.