Lucky Devils casts the mismatched duo as a pair of intrepid newsreel cameramen. When they're not risking their lives coverning the Hot Spots of the world, Dick (Arlen) and Andy (Devine) busy themselves romancing Norma (Dorothy Lovett) and Gwendy (Janet Shaw), respectively.

During World War II, Chinese guerrillas fight against the occupying Japanese forces. A young woman is the secret leader of the villagers, who plot to rescue two downed Flying Tigers pilots, who are currently in the custody of the Japanese. The rescue mission takes on even more importance with the arrival of a Japanese general, which signals a major offensive taking place in the area.