When Nick and Jan move into their new apartment in San Francisco, the batty landlady upstairs tells them about a girl who used to live there in the 20's: a brash young party girl named Maxie, who died in a car crash the morning before her big audition for a Hollywood studio. The trouble is, Maxie, or rather her ghost, hasn't left the house. Worse, she can take over Jan's body. And the only way she's going to leave is if she gets that audition.

Honest and straightforward small-town Shirlee Kenyon chucks her boyfriend and heads for Chicago. Accidentally having to host a radio problem phone-in show, it is clear she is a natural and is hired on the spot. But the station insists she call herself Doctor, and as her popularity grows a local reporter starts digging for the truth. Problem is, the more he is around her the more he fancies her.

Cosmetics mogul Mary Kay Ash faces competition from a driven newcomer, who plots to take apart her control of the makeup industry.

Three female employees of a sexist, egotistical, lying, hypocritical bigot find a way to turn the tables on him.