Attorney Walter Colby has ties to the mob, but he begins to regret his criminal affiliations. When his girlfriend, showgirl Flaxy Martin, who also has shady connections, becomes a suspect in a murder, Walter takes the fall. However, on his way to prison, he escapes, determined to bring the real killer to justice.

In Medicine Bend, a crooked businessman has the town mayor and sheriff in his pocket while his henchmen raid the wagon trains passing through the region.