A group of thieves attempt to rob an art gallery, but when plans backfire and one of the men winds up dead, the group head down south, running afoul of the law. Along the way, they meet up with a seductive con artist with ideas of her own.

Teenage lovers Tony and Tyan-Hwa tip the balance of power in New York's Little Italy and Chinatown.

Julius and Vincent Benedict are the results of an experiment that would allow for the perfect child. Julius was planned and grows to athletic proportions. Vincent is an accident and is somewhat smaller in stature. Vincent is placed in an orphanage while Julius is taken to a south seas island and raised by philosophers. Vincent becomes the ultimate low life and is about to be killed by loan sharks.

Eddie Hawkins, called Hudson Hawk has just been released from ten years of prison and is planning to spend the rest of his life honestly. But then the crazy Mayflower couple blackmail him to steal some of the works of Leonardo da Vinci. If he refuses, they threaten to kill his friend Tommy.