Soldier of fortune, Monroe Bieler, is sent to dole out some American-style justice when the wife and child of an African president are kidnapped by terrorists.

Kickboxing champion Matt Reeves witnesses the murder of his friend Johnny. While investigating the crime, he learns that a Mr. Negaal in South Africa has founded a new kickboxing association and does not leave international champions much of a chance. Johnny had to pay with his life when he did not want to join. Neegal seems to kill everybody who is in his way especially David Sloan from the previous Kickboxer films. Matt is on his own now, but suddenly finds an unexpected ally.

Two former ranking figures of the Axis powers (the evil General Von Rudloff and Japanese master Miyagi) schedule a deadly martial arts tournament in Von Rudloff's desert castle. They race to assemble the top competitors from around the world, with the rebellious Steve Hunt being the most sought after.