出生于室町京都猿乐某个剧团的异形之子犬王（Avu-chan 配音），他被周围的人疏远、戴着遮住面容的葫芦面具。某天，犬王遇到了因诅咒而失明的少年琵琶法师友鱼（森山未来 配音），友鱼弹着琵琶的弦，犬王则踏步而歌。一瞬间，只有两个人的呼吸、只有两人的世界就此展开。犬王享受着壮烈的命运、用强有力的舞蹈开拓出自己人生，身旁的友鱼则探求诅咒的真相、拨弄琵琶与异界共鸣。他们两人成为了在乱世中生存下来的搭档，彼此的才能都得以展现，作为独一无二的艺人使得人们狂热。而在顶点，又有某些东西在等待着他们二人……
影片改编自古川日出男的小说《平家物语 犬王之卷》。

First-year high schooler Midori Asakusa loves anime so much, she insists that "concept is everything" in animation. While she spends her time doodling endless ideas and settings in her sketchbook, she hasn't taken the first step to creating anime, insisting that she can't do it alone. After Asakusa's money-loving best friend Sayaka Kanamori notices her genius and drive – and when it becomes clear that their classmate and charismatic fashion model Tsubame Mizusaki wants to be an animator – the energetic trio start an animation club. Together, the three aim to realize the "ultimate world" that exists in their minds, as they come to see the power that fiction and imagination have on their lives and the world around them.

As a group of university students go out for a night on the town, a sophomore known only as "The Girl with Black Hair" experiences a series of surreal encounters with the local nightlife – all the while unaware of the romantic longings of "Senpai", a senior student who has been creating increasingly fantastic and contrived reasons to run into her in an effort to win her heart.

When a college dropout stops for a late night bite at a mysterious ramen stand, he crosses paths with a self-proclaimed deity of matrimony. This bizarre meeting sends the young man hurtling through a horrifying flashback to his not-so-glorious college days when the influence of a cruel new friend turned him from a hopeless romantic into a mischievous “black cupid.”

片濑高中的新生“阿扁”星野裕（片山福十郎 配音）和“笑爷”月本诚（内山昂辉 配音）是同出自一个乒乓球道场的朋友。阿扁个性张扬，爱说爱笑，由于对球技信心十足，因此根本不把乒乓球部的同期和前辈放在眼里。与之相对，笑爷内敛冷静，对于取胜这件事似乎根本没有半点强烈的欲望，潜意识中他更希望像机器人一般不被人注意到。为了迎接即将到来的高中联赛，乒乓球部顾问小泉老师（屋良有作 配音）选定月本进行操练。与此同时，附近的辻堂学院高中转来了被踢出国家队的中国选手孔文革（文晔星 饰），此人恃才傲物，完全不把技术底下的日本选手放在眼里。另一方面，高手云集的海王学院高中也蓄势待发，备战接下来的大赛。方寸球桌，战况激烈……
本片根据松本大洋的同名原作改编。

Space Dandy is a dandy guy, in space! This dreamy adventurer with a to-die-for pompadour travels across the galaxy in search of aliens no one has ever laid eyes on. Each new species he discovers earns him a hefty reward, but this dandy has to be quick on his feet because it's first come, first served! Accompanied by his sidekicks, a rundown robot named QT and Meow the cat-looking space alien, Dandy bravely explores unknown worlds inhabited by a variety of aliens. Join the best dressed alien hunter in all of space and time as he embarks on an adventure that ends at the edge of the universe!